Software:IGB
From BioInfo
The Integrated Genome Browser (IGB) is a highly sophisticated, cross platform, stand alone genome browser designed for real time visualization and manipulation of large genomic datasets (tiling, expression, chIP, copy number, snp, next generation sequencing...). Although written primary through external grants administered by Affymetrix, IGB is open source and supports most major binary and text file data formats.
Primary development of IGB is being coordinated through Ann Loraine's BioViz group at UNC and the Genoviz SourceForge project site.
[edit] Details/ Resources
- BioViz IGB Web site
- Genoviz IGB Web site
- Affy IGB web site
- Old User Guide
- Bug Reports
- Feature Requests
- General Help Requests
[edit] To Launch the U of U Beta verison of IGB
- Launch IGB by clicking one of the following Java Web Start links based on the amount of memory in your computer.
- NOTE - If IGB does not launch, try one of the links with the smaller memory requirements.
- If you have a restricted account on the UofUtah DAS/2 GenoPub server, authenticate at the prompt. Our DAS/2 URL is http://bioserver.hci.utah.edu:8080/DAS2DB/genome . Browse the files within from GenoPub, http://bioserver.hci.utah.edu:8080/DAS2DB/genopub .
[edit] Tips
- No Java 1.6 installed? Get it free from http://www.java.com/en/download/
- Problem getting java 1.6 on older Macs? See http://landonf.bikemonkey.org/static/soylatte/
Note that the soylatte distribution of java 1.6 does not include java web start. Web start is the typical mechanism for starting IGB, and without web start you will need to create a script to launch IGB. In addition, soylatte assumes XWindows X11R6 is installed and running on the Mac.
- When moving to the most recent versions of IGB and especially if odd behavior is observed:
- Attempt to clear the cache and reset the preferences from within a running version of IGB (File-> Preferences-> Data Sources-> Clear Cache; File-> Preferences-> Other Options-> Reset all preferences to defaults). Restart. If that fail try the following.
- Delete the IGB Cache folder from your home directory (this will clear any bookmarks and cached data)
- MacOSX: UserHome/.igb
- XP: UserHome/Application Data/IGB
- Note: These directories are hidden so you will need to enable viewing of hidden files or delete them from the command line
- Delete the IGB Cache folder from your home directory (this will clear any bookmarks and cached data)
- If you cannot launch IGB to reset the preferences, on Macs, delete all of the UserHome/Library/Preferences/com.affymetrix.* file(s) and relaunch
- If you still cannot launch IGB, you can run IGB Clear Cache first. Now launch IGB the normal way.
- Attempt to clear the cache and reset the preferences from within a running version of IGB (File-> Preferences-> Data Sources-> Clear Cache; File-> Preferences-> Other Options-> Reset all preferences to defaults). Restart. If that fail try the following.
- Synonyms- When uploading data to IGB from your computer, it often reads the versioned genome information in the file. Unfortunately, there are many different names used to indicate a particular genome build (ie hg18, NCBI36.1, NCBIBuild36.1, H_sapiens_Mar_2006). If you are having difficulty getting IGB to load data into a particular genome build it may help to load a personal synonyms.txt file (tab delimited, each line represents a group of synonyms). Download this file by right clicking, modify it to suit then, in IGB, goto File -> Preferences -> Data Sources -> Personal Synonyms File -> Browse -> Load Synonyms.
